Rupniak, N M : rechercher sur Z-Library

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1

Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders

Andrew Holmes, Markus Heilig, Nadia M.J. Rupniak, Thomas Steckler, Guy Griebel

Journal:

Trends in Pharmacological Sciences

Année:

2003

Langue:

english

Fichier:

PDF, 1.41 MB

english, 2003

2

New insights into the antidepressant actions of substance P (NK 1 receptor) antagonists

Rupniak, Nadia M.J

Journal:

Canadian Journal of Physiology and Pharmacology

Année:

2002

Fichier:

PDF, 123 KB

2002

3

Novel strategies for pharmacotherapy of depression

Karen A Maubach, Nadia MJ Rupniak, Mark S Kramer, Raymond G Hill

Journal:

Current Opinion in Chemical Biology

Année:

1999

Langue:

english

Fichier:

PDF, 914 KB

english, 1999

4

Evidence for antidepressant and anxiolytic activity of substance P antagonists in preclinical assays

N.J. Rupniak, E. Carlson, D. Smith, T. Harrison, C. Swain, M. Cascieri, G. Chicchi, S. Sadowski, J. Hale, S. Mills, M. MacCoss, R. Hargreaves

Journal:

Psychoneuroendocrinology

Année:

2000

Langue:

english

Fichier:

PDF, 103 KB

english, 2000

5

Clinical evidence that substance P antagonists are well-tolerated antidepressants

Mark S. Kramer, Neal Cutler, John Feighner, Ram Shrivastava, John Carman, Guanghan Liu, Duane Snavely, Edwina Wyatt-Knowles, Scott Reines, Nadia Rupniak

Journal:

Psychoneuroendocrinology

Année:

2000

Langue:

english

Fichier:

PDF, 93 KB

english, 2000

6

Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression

M. Guscott, L.J. Bristow, K. Hadingham, T.W. Rosahl, M.S. Beer, J.A. Stanton, F. Bromidge, A.P. Owens, I. Huscroft, J. Myers, N.M. Rupniak, S. Patel, P.J. Whiting, P.H. Hutson, K.C. Fone, S.M. Biello,

Journal:

Neuropharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 444 KB

english, 2005

7

Discovery of the antidepressant and anti-emetic efficacy of substance P receptor (NK1) antagonists

Nadia M.J Rupniak, Mark S Kramer

Journal:

Trends in Pharmacological Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 167 KB

english, 1999

8

36. Clinical profile of substance P antagonists

M.S. Kramer, N.R. Cutler, J. Feighner, R. Shrivastava, J.S. Carman, G. Liu, D. Snavely, E. Wyatt-Knowles, S.A. Reines, N.M. Rupniak

Journal:

Biological Psychiatry

Année:

2000

Langue:

english

Fichier:

PDF, 20 KB

english, 2000

9

NK1 receptor antagonists for depression: Why a validated concept was abandoned

Rupniak, Nadia M.J., Kramer, Mark S.

Journal:

Journal of Affective Disorders

Année:

2017

Langue:

english

Fichier:

PDF, 205 KB

english, 2017

10

Dystonia induced by combined treatment with L-dopa and MK-801 in parkinsonian monkeys

Dr. N. M. J. Rupniak, S. Boyce, M. J. Steventon, S. D. Iversen, C. D. Marsden

Journal:

Annals of Neurology

Année:

1992

Langue:

english

Fichier:

PDF, 348 KB

english, 1992

11

Spirocyclic NK1 Antagonists. Part 2. [4.5]-Spiroethers.

Brian J. Williams, Margaret A. Cascieri, Gary G. Chicchi, Timothy Harrison, Andrew P. Owens, Simon N. Owen, Nadia M. J. Rupniak, David F. Tattersall, Angela Williams, Christopher J. Swain

Journal:

Année:

2003

Fichier:

PDF, 79 KB

2003

12

Species differences in tachykinin receptor distribution: Further evidence that the substance P (NK1) receptor predominates in human brain

Michael Rigby, Ruth O'Donnell, Nadia M.J. Rupniak

Journal:

The Journal of Comparative Neurology

Année:

2005

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2005

13

Profile of cholinomimetic drugs in primates: Status of screens for potential Alzheimer therapies

Nadia M. J. Rupniak

Journal:

Drug Development Research

Année:

1992

Langue:

english

Fichier:

PDF, 886 KB

english, 1992

14

Concentration and time-dependent inter-relationships for antitumour drug cytotoxicities against tumour cells in vitro

H. Thomas Rupniak, Richard D. H. Whelan, Bridget T. Hill

Journal:

International Journal of Cancer

Année:

1983

Langue:

english

Fichier:

PDF, 550 KB

english, 1983

15

Establishment and characterisation of three new human ovarian carcinoma cell lines and initial evaluation of their potential in experimental chemotherapy studies

Bridget T. Hill, Richard D. H. Whelan, Elizabeth M. Gibby, Louise K. Hosking, H. Thomas Rupniak, Denise Sheer, Sharon A. Shellard

Journal:

International Journal of Cancer

Année:

1987

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1987

16

Inhibition of spermidine and spermine synthesis leads to growth arrest of rat embryo fibroblasts in G1

H. T. Rupniak, D. Paul

Journal:

Journal of Cellular Physiology

Année:

1978

Langue:

english

Fichier:

PDF, 909 KB

english, 1978

17

Lack of a correlation between polyamine synthesis and DNA synthesis by cultured rat liver cells and fibroblasts

H. T. Rupniak, D. Paul

Journal:

Journal of Cellular Physiology

Année:

1978

Langue:

english

Fichier:

PDF, 290 KB

english, 1978

18

Spontaneous orofacial dyskinesias in a captive cynomolgus monkey: Implications for tardive dyskinesia

Dr. N. M. J. Rupniak, S. J. Tye, M. J. Steventon, S. Boyce, S. D. Iversen

Journal:

Movement Disorders

Année:

1990

Langue:

english

Fichier:

PDF, 517 KB

english, 1990

19

Nociception and inflammatory hyperalgesia in B2 bradykinin receptor knockout mice

Susan Boyce, Nadia M.J. Rupniak, Emma J. Carlson, Janine Webb, Joseph A. Borkowski, J. Fred Hess, Catherine D. Strader, Raymond G. Hill

Journal:

Immunopharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 202 KB

english, 1996

20

Spirocyclic NK1 antagonists II: [4.5]-spiroethers

Brian J. Williams, Margaret A. Cascieri, Gary G. Chicchi, Timothy Harrison, Andrew P. Owens, Simon N. Owen, Nadia M.J. Rupniak, David F. Tattersall, Angela Williams, Christopher J. Swain

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 117 KB

english, 2002

21

Increased neurogenesis and brain-derived neurotrophic factor in neurokinin-1 receptor gene knockout mice

Sara Morcuende, Christopher A. Gadd, Marco Peters, Andrew Moss, Elizabeth A. Harris, Anne Sheasby, Amy S. Fisher, Carmen De Felipe, Patrick W. Mantyh, Nadia M. J. Rupniak, K. Peter Giese, Stephen P. H

Journal:

European Journal of Neuroscience

Année:

2003

Langue:

english

Fichier:

PDF, 257 KB

english, 2003

22

Acute dystonia induced by neuroleptic drugs

N. M. J. Rupniak, P. Jenner, C. D. Marsden

Journal:

Psychopharmacology

Année:

1986

Langue:

english

Fichier:

PDF, 2.00 MB

english, 1986

23

A comparative assessment of the in vitro effects of drugs on cells by means of colony assays or flow microfluorimetry

Bridget T. Hill, Richard D. H. Whelan, H. Thomas Rupniak, Lorraine Y. Dennis, Mary A. Rosholt

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1981

Langue:

english

Fichier:

PDF, 470 KB

english, 1981

24

Pharmacological characterisation of spontaneous or drug-associated purposeless chewing movements in rats

N. M. J. Rupniak, P. Jenner, C. D. Marsden

Journal:

Psychopharmacology

Année:

1985

Langue:

english

Fichier:

PDF, 989 KB

english, 1985

25

Cholinergic manipulation of perioral behaviour induced by chronic neuroleptic administration to rats

N. M. J. Rupniak, P. Jenner, C. D. Marsden

Journal:

Psychopharmacology

Année:

1983

Langue:

english

Fichier:

PDF, 597 KB

english, 1983

26

Differential alterations in striatal dopamine receptor sensitivity induced by repeated administration of clinically equivalent doses of haloperidol, sulpiride or clozapine in rats

N. M. J. Rupniak, G. Kilpatrick, M. D. Hall, P. Jenner, C. D. Marsden

Journal:

Psychopharmacology

Année:

1984

Langue:

english

Fichier:

PDF, 957 KB

english, 1984

27

Differential effects of continuous administration for 1 year of haloperidol or sulpiride on striatal dopamine function in the rat

N. M. J. Rupniak, S. Mann, M. D. Hall, S. Fleminger, G. Kilpatrick, P. Jenner, C. D. Marsden

Journal:

Psychopharmacology

Année:

1984

Langue:

english

Fichier:

PDF, 1.06 MB

english, 1984

28

Comparison of the effects of four cholinomimetic agents on cognition in primates following disruption by scopolamine or by lists of objects

N. M. J. Rupniak, M. J. Steventon, M. J. Field, C. A. Jennings, S. D. Iversen

Journal:

Psychopharmacology

Année:

1989

Langue:

english

Fichier:

PDF, 828 KB

english, 1989

29

Alterations in cerebral glutamic acid decarboxylase and3H-flunitrazepam binding during continuous treatment of rats for up to 1 year with haloperidol, sulpiride or clozapine

N. M. J. Rupniak, S. A. Prestwich, R. W. Horton, P. Jenner, C. D. Marsden

Journal:

Journal of Neural Transmission

Année:

1987

Langue:

english

Fichier:

PDF, 669 KB

english, 1987

30

Mesolimbic dopamine function is not altered during continuous chronic treatment of rats with typical or atypical neuroleptic drugs

Nadia M. J. Rupniak, M. D. Hall, E. Kelly, S. Fleminger, G. Kilpatrick, P. Jenner, C. D. Marsden

Journal:

Journal of Neural Transmission

Année:

1985

Langue:

english

Fichier:

PDF, 996 KB

english, 1985

31

Drug-induced purposeless chewing: animal model of dyskinesia or nausea?

N. M. J. Rupniak, S. J. Tye, S. D. Iversen

Journal:

Psychopharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 423 KB

english, 1990

32

Lack of effect of CCKBreceptor antagonists in ethological and conditioned animal screens for anxiolytic drugs

Gerard R. Dawson, Nadia M. J. Rupniak, Susan D. Iversen, Rachel Curnow, Spencer Tye, Kelly J. Stanhope, Mark D. Tricklebank

Journal:

Psychopharmacology

Année:

1995

Langue:

english

Fichier:

PDF, 1.35 MB

english, 1995

33

Characterisation of dyskinesias induced byl-dopa in MPTP-treated squirrel monkeys

S. Boyce, N. M. J. Rupniak, M. J. Steventon, S. D. Iversen

Journal:

Psychopharmacology

Année:

1990

Langue:

english

Fichier:

PDF, 747 KB

english, 1990

34

Oxidative neuropathology and putative chemical entities for alzheimer’s disease: Neuroprotective effects of salen-manganese catalytic anti-oxidants

H. Thomas R. Rupniak, Ken A. Joy, Charlotte Atkin, Gill Brown, Julie C. Barnes, Susan R. Doctrow, Bernard Malfroy, Tony Wong, Ian K. Anderson, Chris R. Molloy, Gary I. Mills, Peter Soden

Journal:

Neurotoxicity Research

Année:

2000

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2000

35

Chronic psychosocial stress in tree shrews: effect of the substance P (NK1receptor) antagonist L-760735 and clomipramine on endocrine and behavioral parameters

Marieke G. C. van der Hart, Gabriel de Biurrun, Boldizsár Czéh, Nadia M. J. Rupniak, Johan A. den Boer, Eberhard Fuchs

Journal:

Psychopharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 318 KB

english, 2005

36

Enhanced performance of spatial and visual recognition memory tasks by the selective acetylcholinesterase inhibitor E2020 in rhesus monkeys

N. M. J. Rupniak, Spencer J. Tye, Mark J. Field

Journal:

Psychopharmacology

Année:

1997

Langue:

english

Fichier:

PDF, 227 KB

english, 1997

37

Simple Assays of Retinoid Activity as Potential Screens for Compounds That May Be Useful in Treatment of Psoriasis.

West, Michael R., Page, Joanna M., Turner, David M., Wood, Edward J., Holland, Diana B., Cunliffe, William J., Rupniak, H. Thomas

Journal:

The Journal of Investigative Dermatology

Année:

1992

Fichier:

PDF, 3.52 MB

1992

38

Cell cycle regulation by growth factors and nutrients in normal and transformed cells

Dieter Paul, Kenneth D. Brown, H. Thomas Rupniak, H. J. Ristow

Journal:

In Vitro Cellular & Developmental Biology - Plant

Année:

1978

Langue:

english

Fichier:

PDF, 722 KB

english, 1978

39

Cognitive impairment in schizophrenia: How experimental models using nonhuman primates may assist improved drug therapy for negative symptoms

N.M.J. Rupniak, S.D. Iversen

Journal:

Neuropsychologia

Année:

1993

Langue:

english

Fichier:

PDF, 1.24 MB

english, 1993

40

Anxiolytic-like and antinociceptive effects of MK-801 accompanied by sedation and ataxia in primates

N.M.J. Rupniak, S. Boyce, S. Tye, G. Cook, S.D. Iversen

Journal:

Pharmacology Biochemistry and Behavior

Année:

1993

Langue:

english

Fichier:

PDF, 378 KB

english, 1993

41

Antinociceptive effects of racemic RP67580, but not racemic CP96345, on acetic acid-induced writhing and formalin paw in mice

S. Boyce, N.M.J. Rupniak, L. Young, W. Rycroft, L. Bristow, S.D. Iversen, R.G. Hill

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 127 KB

english, 1992

42

Failure of intravenous pentagastrin challenge to induce panic-like effects in rhesus monkeys

N.M.J. Rupniak, L. Schaffer, P. Siegl, S.D. Iversen

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 399 KB

english, 1993

43

Non-specific antinociceptive effects of CP-99,994

S. Boyce, N.M.J. Rupniak, A.R. Williams, S.D. Iversen, R.G. Hill

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 132 KB

english, 1993

44

Mechanisms of action of the antidepressants fluoxetine and the substance P antagonist L-000760735 are associated with altered neurofilaments and synaptic remodeling

Paul C Guest, Michael R Knowles, Sylvain Molon-Noblot, Kamran Salim, David Smith, Fraser Murray, Philippe Laroque, Stephen P Hunt, Carmen de Felipe, Nadia M Rupniak, George McAllister

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 795 KB

english, 2004

45

Evaluation of the mGlu8 receptor as a putative therapeutic target in schizophrenia

Melanie J. Robbins, Kathryn R. Starr, Andy Honey, Ellen M. Soffin, Claire Rourke, Gareth A. Jones, Fiona M. Kelly, Jay Strum, Rosemary A. Melarange, Andy J. Harris, Magalie Rocheville, Tom Rupniak, Pa

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 546 KB

english, 2007

46

Anxiolytic actions of the substance P (NK1) receptor antagonist L-760735 and the 5-HT1A agonist 8-OH-DPAT in the social interaction test in gerbils

S Cheeta, S Tucci, J Sandhu, A.R Williams, N.M.J Rupniak, S.E File

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 254 KB

english, 2001

47

Evidence for recovery of spatial learning following entorhinal cortex lesions in mice

R. Hardman, D.J. Evans, L. Fellows, B. Hayes, H.T. Rupniak, J.C. Barnes, G.A. Higgins

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 3.52 MB

english, 1997

48

Behavioural analysis and susceptibility to CNS injury of four inbred strains of mice

Stephen J Royle, Fiona C Collins, H.Tom Rupniak, Julie C Barnes, Richard Anderson

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 2.43 MB

english, 1999

49

The substance P antagonist L-760,735 inhibits stress-induced NK1 receptor internalisation in the basolateral amygdala

D.W Smith, L Hewson, P Fuller, A.R Williams, A Wheeldon, N.M.J Rupniak

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 1.46 MB

english, 1999

50

Apolipoprotein E and Alzheimer's Disease: A Review of Recent Studies

Guy A Higgins, Charles H Large, H.Thomas Rupniak, Julie C Barnes

Journal:

Pharmacology Biochemistry and Behavior

Année:

1997

Langue:

english

Fichier:

PDF, 294 KB

english, 1997